Program

Workshop Rome, June 18-20, 2009.
“The Role of Autophagy in Infectious Diseases and Cancer”

National Institute for Infectious Diseases “Lazzaro Spallanzani”

Chairs
Gian Maria Fimia and Mauro Piacentini

Thursday, June 18.

17.45 Welcome and Opening Remarks
       Dr. Giuseppe Ippolito
       Scientific Director of National Institute for Infectious Diseases “Lazzaro Spallanzani”

Molecular mechanisms of autophagy

18.00 Beth Levine (USA)
        ”Autophagy genes protect against cancer and infectious diseases”

18.30 David C. Rubinsztein (U.K)
        ”Autophagic clearance of Aggregate-Prone Proteins: relevance for disease pathogenesis and therapeutic strategies”

19.00 Sharon A. Tooze
        ”Trafficking and signalling in Autophagy”

19.30 Welcome cocktail

Friday, June 19.

9.30 Fulvio Reggiori (Netherlands)
      ”Autophagosomes and other double-membrane vesicles. all the same?”

10.00 Adi Kimchi (Israel)
        ”Mechanistic links between DAP-kinase and autophagy”.

10.30 Gian Maria Fimia (Italy)
        ”Regulation of Ambra1-dependent autophagy”

11.00 Coffee Break

Autophagy in Infectious Diseases

11.30 Vojo Deretic (USA)
        ”Links between innate and adaptive immunity and autophagy”

12.00 Audrey Esclatine (France)
        ”Insights into the mechanism of human cytomegalovirus-mediated inhibition of autophagy.”

12.30 Martine Biard-Piechaczyk (France)
        ”Autophagy during HIV-1 infection of CD4 T cells”

 

13.00  Lunch

Autophagy and Cancer

14.30 Marja Jäättelä (Denmark)
        ”Regulation of autophagy by kinases and phosphatases”

15.00 Guillermo Velasco (Spain)
        ”Role of autophagy in cannabinoid antitumoral action”

15.30 Hans-Uwe Simon (Switzerland)
        ”Cancer cell death regulation by autophagy”.

16.00  Coffee break

Autophagy and Cancer

16.30 Francesco Cecconi (Italy)
        ”Regulation of Ambra1-dependent autophagy in development and disease”

17.00 Walter Malorni (Italy)
         “Xenophagy: an exacerbation of autophagy?

17.30 Anne Simonsen (Norway)
        ”Alfy is selectively required for protein accumulation-mediated autophagy”

18.00 Penny Lovat (UK)
        ”Oncogenic B-RAF signalling confers the resistance of metastatic melanoma to autophagy”

18.30 Matthias Peter (Switzerland)
        ”Selective degradation of ribosomes by a ubiquitin-dependent mechanism in yeast and mammalian cells “

19.00  Concluding remarks and network discussion
          Mauro Piacentini

20.30 Dinner